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The 3rd Edition (M45-Ed3) was published in 2016, with ongoing updates, including emerging data on Pseudomonas species other than P. aeruginosa (POPA) planned for a 4th edition.
Disclaimer: CLSI guidelines are copyrighted and regularly updated. Always refer to the most recent edition of CLSI M45 published by the Clinical and Laboratory Standards Institute. This article is for informational purposes and does not replace professional medical or laboratory advice.
Ensures clinicians receive reliable data to guide targeted antibiotic therapy. clsi document m45 pdf
Unlike standard pathogens, fastidious organisms cannot simply be tested on standard Mueller-Hinton agar incubated in ambient air. CLSI M45 details modifications such as:
Which are you looking to test?
Always check that your laboratory standard operating procedures (SOPs) match the current active edition of the M45 document.
Disclaimer: This article is for informational purposes. Always refer to the latest, official CLSI documents for clinical laboratory practices. The 3rd Edition (M45-Ed3) was published in 2016,
: "Breakpoints" (susceptible, intermediate, or resistant) tailored to the unique growth characteristics of these bacteria.
Each organism section provides specific recommendations for: Always refer to the most recent edition of
Guides labs on which drugs are appropriate for testing specific, less common pathogens.